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How to Prepare for Your Weekly Injection

Learn how to safely prepare and administer your weekly injection with step-by-step guidance on site selection, dosage preparation, and injection technique. Follow proper storage, rotation, and disposal instructions for safe treatment.

This guide explains how to safely prepare and administer your weekly subcutaneous injection.

1. Before you begin

  • Wash your hands thoroughly with soap and warm water for at least 20 seconds, then dry with a clean towel

  • Gather your supplies (syringe, alcohol swabs, medication vial, sharps container)

  • Review your prescribed dose and instructions provided by your pharmacy or licensed provider

2. Select and prepare your injection site

Choose one of the following areas:

  • Abdomen (stomach): 2–3 inches away from the navel (most common)

  • Front of upper thigh

  • Back of upper arm (usually if assisted)

Note: Choose soft fatty tissue, not muscle.

Clean the site with an alcohol swab and allow it to air dry. Do not touch, fan, or blow on the area after cleaning.

3. Rotate injection sites

  • Do not inject in the exact same spot each week

  • Stay within the same general area if preferred, but move at least 1–2 inches from the previous injection site

  • This helps reduce irritation, lumps, and absorption issues

4. Prepare the syringe

Important Safety Note: Always verify the prescription label on your medication before injecting. The label contains your prescribed dose and the exact number of units you should take.

  • Draw air into the syringe equal to your prescribed dose

  • Inject the air into the vial to make drawing medication easier

  • Turn the vial upside down and draw the correct dose

  • Tap the syringe to remove air bubbles and adjust to the exact amount

5. Administer the injection

  • Gently pinch the skin

  • Insert the needle at a 90° angle (or 45° if you are very lean)

  • Inject slowly and steadily until all medication is delivered

6. After injection

  • Remove the needle straight out

  • Do not rub the injection site (this may cause irritation)

  • Lightly press with clean gauze if needed

7. Dispose safely

  • Immediately place the syringe into a sharps container

  • Do not reuse needles or syringes

Important Information

Proper injection technique, site rotation, and safe disposal are essential to ensure correct dosing and reduce the risk of irritation or complications.

  • Take your injection once weekly on the same day each week

  • Can be taken with or without food

  • If you miss a dose: take it within 96 hours (4 days); otherwise skip

  • Mild redness or slight swelling may be normal

  • Severe pain, swelling, or persistent redness should be reported to your provider

  • Store medication as instructed (usually refrigerated; do not freeze)

Need Additional Help?

If you have any more questions, you can contact the Mevo Health support team through live chat.

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