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How Does Semaglutide Work?

A simple explanation of how semaglutide helps with weight loss.

Maya avatar
Written by Maya
Updated over 2 weeks ago

Semaglutide is a medication that helps your body naturally control hunger and stabilize appetite.


It’s part of a class of medications called GLP-1 receptor agonists, which means it works by copying the action of a hormone your body already makes.

What semaglutide does inside your body

Semaglutide helps with weight loss by:

  • Reducing your appetite: you feel full sooner

  • Lowering cravings: especially for snacks or late-night eating

  • Slowing down digestion: meals keep you fuller for longer

  • Improving insulin response: leads to more stable blood sugar and fewer energy crashes

  • Calming “food noise”: many patients say they finally stop thinking about food all day

It’s not a stimulant. It doesn’t speed up your heart or make you jittery.
It simply gives your brain and stomach a better ability to regulate appetite and portion sizes.

What results can you expect

Semaglutide has been shown to help most patients lose:

  • 10–15% of their total body weight over 6–12 months

Your exact results depend on:

  • Your dose

  • How consistent you are

  • Your body’s metabolism

  • Lifestyle habits (sleep, hydration, eating speed, etc.)

The weight loss happens gradually and steadily, which is healthier and easier to maintain long-term.

How you take semaglutide

You’ll take semaglutide once a week using a very small needle.
The injection goes just under the skin (belly, thigh, or arm).

Most patients say:

  • “It felt like a tiny pinch.”

  • “Much easier than a vaccine.”

  • “I didn’t feel anything at all.”

You’ll get step-by-step instructions from the Mevo Health team.

Why many patients love semaglutide

Patients often describe semaglutide as:

  • “Quieting my appetite for the first time in years”

  • “Helping me feel in control of food—not the other way around”

  • “Making healthy choices surprisingly easy”

While it’s a powerful medication, the goal is to support sustainable, long-term change, not crash dieting.

Your Mevo Health provider will guide your dose, monitor your progress, and help you every step of the way.

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